El up to Lem are usually considered to be low runes, Pul to Gul are usually considered to be mid runes buy d2r items, while Vex through Zod are generally considered high runes. If you encounter the mid or high runs in your travels, be sure not to part with them readily!
Runewords are some of the most powerful items you can craft in Diablo 2: Resurrected, although they take quite the effort to create. First, you need to find the appropriate runes in order to create the runeword. Then, you must find the corresponding weapon or shield that can accept the runeword.
The item must have the right number of sockets for the word to work, and the runes have to be placed in the item that is socketed in the correct order. The item must also be unadorned (white) as well as magic (blue) and rare (yellow), unique (gold) in addition to set (green) items that have the right amount of sockets won't work with runewords.
This is why you need to take great attention when making a runeword. Doubleand triple check that the object's name is correct- for example, the Insight runeword can be created with polearms and staves D2R ladder items buy, but not spears . put the runes out in the proper sequence before attaching them to the item.